Recipient of the Robert Guthrie Award 2005<\/h2>
Benjamin Jos\u00e9 Schmidt who passed away on June 6, 2009, was a pediatrician, graduated from Medicine School of S\u00e3o Paulo University (USP), Brazil, in 1955. He started his university career in 1958 at Escola Paulista de Medicina (EPM), also Known as Federal University of S\u00e3o Paulo (UNIFESP), reaching the position of Chair Professor of Social Pediatric.<\/p>
Together with his colleagues Aron Diament and Oswaldo Cruz, he founded the Lavoisier Laboratory in 1952, which is one of the most respected in S\u00e3o Paulo. In the beginnings of the 60\u00b4s, they started research on some Inborn Errors of Metabolism (IEM). Dr.Schmidt has done voluntary work at the Habilitation Center of the APAE (Association of Parents and Friends of the Mentally Handicapped) in S\u00e3o Paulo, an institution founded in 1961.<\/p>
Always with the interest focused on IEM, he created, in 1976 at APAE, a laboratory for the research of hyperphenylalaninemia, especially phenylketonuria. Together with Dr. Stanislau Krinsky, pediatrician and APAE\u00b4s clinic director, and the neurologist Dr. Aron Diament, he had started since 1973 the project for \u201ca National Plan for Study and Detection on Inborn Errors of Metabolism Disorders that could lead to mental deficiency\u201d, which was presented at the Federation of APAE\u00b4s Congress, held in Porto Alegre (RS-Brazil). This was the proposal for the installation and functioning of the first specialized center for the population screening of phenylketonuria, as a form of prevention of mental deficiency, after one World Health Organization recommendation since 1968.<\/p>
The center used the Guthrie technique for collection of blood samples on filter paper (DBS). Until then in all labs in the world, phenylalanine was identified through a semiquantitative methodology (the Guthrie bacterial inhibition assay using bacillus subtilis). However, at APAE SP a quantitative adapted fluorimetric auto-analyzer was employed for the first time in the history. With the implementation of the phenylalanine dosing through this equipment, the first Newborn Screening Program for Inborn Errors of Metabolism in Latin America was initiated.
In order to provide a better and wider support to the detected patients, Drs. Schmidt, Krinsky and Diament created at APAE\u00b4s Ambulatory, the first Multidisciplinary Team.
In complement to the screening program, Benjamin Schmidt obtained from Nestle, which produced in Europe the phenylalanine-free ASP milk, the commitment of enough milk free supply donation for treatment of the first 100 cases detected.<\/p>
In 1976 the Phenylketonuria Newborn Screening Program, extended its research towards the detection also of congenital hypothyroidism in newborns by the measurement of T4 in the same blood spot sample.<\/p>
In the next decade, other institutions followed the APAE SP\u00b4s example and started their newborn screening programs in other Brazilian States. Since the beginning of the 80\u00b4s, a group formed by experts on Newborn Screening in the world, among them Drs. H. Naruse, R. Guthrie, H. Bickel and B. Schmidt, exchanged letters and gathered regularly.
During the 6th International Screening Symposium of Inborn Errors of Metabolism\u201d \u2013 1986 \u2013 Austin \u2013 TX \u2013 it was proposed to organize the \u201c1st Workshop of Quality Control in Neonatal Screening\u201d in Nikko\/Japan in 1987. In this last workshop the founding of the \u201cInternational Society for Newborn Screening\u201d was decided.
The first official meeting of the ISNS was held in 1988 at S\u00e3o Paulo\/Brazil, during the \u201c7th International Screening Symposium of Inborn Errors of Metabolism\u201d, by invitation of the APAE de S\u00e3o Paulo, then represented by Prof. Benjamin Schmidt.<\/p>
In July, 13, 1990, a federal law, (Law N\u00ba 8069), established as mandatory in all Brazil, the execution of examinations towards the detection and treatment of metabolism anomalies in newborns, as idealized by Dr. Schmidt in 1973. Brazil was the first country in Latin America to pass such a law.
Dr. Schmidt participated in the creation of SLEIMPN (the Latin American Society of Inborn Errors of Metabolism and Neonatal Screening). This society is very important in helping countries in Latin America that in 2005 still have no neonatal screening programme.<\/p>
In 1999 the Brazilian Society of newborn Screning was founded. For its biannual meetings it established a prize for the best submitted work, called \u201cBenjamin Schmidt \u2013 a pioneer\u201d.<\/p><\/div> <\/div>\n <\/div>\n <\/div>\n<\/div>
![\"h_levy_2-1\"](\"https:\/\/www.isns-neoscreening.org\/wp-content\/uploads\/2020\/10\/h_levy_2-1.jpg\")
<\/div><\/div>![\"benjamin_schmidt_2-300x200\"](\"https:\/\/www.isns-neoscreening.org\/wp-content\/uploads\/2020\/10\/benjamin_schmidt_2-300x200-1.jpg\")
<\/div>Recipient of the Robert Guthrie Award 2005Benjamin Jos\u00e9 Schmidt who passed away on June 6, 2009, was a pediatrician, graduated from Medicine School of S\u00e3o Paulo University (USP), Brazil, in 1955. He started his university career in 1958 at Escola Paulista de Medicina (EPM), also Known as Federal University of S\u00e3o Paulo (UNIFESP), reaching the position of Chair Professor of Social Pediatric.Together with his colleagues Aron Diament and Oswaldo Cruz, he founded the Lavoisier Laboratory in 1952, which is one of the most respected in S\u00e3o Paulo. In the beginnings of the 60\u00b4s, they started research on some Inborn Errors of Metabolism (IEM). Dr.Schmidt has done voluntary work at the Habilitation Center of the APAE (Association of Parents and Friends of the Mentally Handicapped) in S\u00e3o Paulo, an institution founded in 1961.Always with the interest focused on IEM, he created, in 1976 at APAE, a laboratory for the research of hyperphenylalaninemia, especially phenylketonuria. Together with Dr. Stanislau Krinsky, pediatrician and APAE\u00b4s clinic director, and the neurologist Dr. Aron Diament, he had started since 1973 the project for \u201ca National Plan for Study and Detection on Inborn Errors of Metabolism Disorders that could lead to mental deficiency\u201d, which was presented at […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":966,"menu_order":9,"comment_status":"closed","ping_status":"closed","template":"template-parts\/page-builder.php","meta":{"inline_featured_image":false,"footnotes":""},"tags":[],"class_list":["post-925","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.isns-neoscreening.org\/es\/wp-json\/wp\/v2\/pages\/925","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.isns-neoscreening.org\/es\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.isns-neoscreening.org\/es\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.isns-neoscreening.org\/es\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.isns-neoscreening.org\/es\/wp-json\/wp\/v2\/comments?post=925"}],"version-history":[{"count":1,"href":"https:\/\/www.isns-neoscreening.org\/es\/wp-json\/wp\/v2\/pages\/925\/revisions"}],"predecessor-version":[{"id":1162,"href":"https:\/\/www.isns-neoscreening.org\/es\/wp-json\/wp\/v2\/pages\/925\/revisions\/1162"}],"up":[{"embeddable":true,"href":"https:\/\/www.isns-neoscreening.org\/es\/wp-json\/wp\/v2\/pages\/966"}],"wp:attachment":[{"href":"https:\/\/www.isns-neoscreening.org\/es\/wp-json\/wp\/v2\/media?parent=925"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.isns-neoscreening.org\/es\/wp-json\/wp\/v2\/tags?post=925"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}